ࡱ>  7bjbjUU 4??  EEEEEYYY8UY7e6g6g6g6g6g6g6$l9<\6E6EEx7HHHXEEe6He6HHc1S3U(YX2Q670726j<fj<,S3S3j<EI4H667j< : CURRICULUM VITAE Name: Benjamin Samuel Weeks, Ph.D. Contact: email:  HYPERLINK "mailto:weeks@adelphi.edu" weeks@adelphi.edu phone: 516-877-4193 Title: Professor of Biology, 鶹ֱ Education: 1984, B.A., Biology and Philosophy Dual Major, Skidmore College 1988, Ph.D., Molecular Cell Biology, University of Connecticut Chronology of Employment: 19881993: National Institutes of Health, NIDR, Laboratory of Developmental Anomalies, Postdoctoral fellow 19931995: Hamilton College, Biology Department, Assistant Professor of Biology 19951997: University of Pennsylvania, Department of Medicine, Assistant Professor of Medicine 19972002: 鶹ֱ, Biology Department, Assistant Professor of Biology 2002-2006: 鶹ֱ, Biology Department, Associate Professor of Biology 2006-present: 鶹ֱ, Biology Department, Professor of Biology Awards/Funding/Resources: 1989 - 1991: National Institute of Dental Research (NIDR) Performance Award (received annually). 1991  1993: National Research Service Award, National Institutes of Health grant number DE05599, $100,000.00. 2000: Misonix Incorporated, The HIV-1 coat protein, gp120, promotes HSV-1 pathogenesis, $6,700.00 awarded in the form of equipment. 2000: 鶹ֱ Presidential Award, Nerve regeneration: A role for nitric oxide?, $2,500.00 2001: 鶹ֱ Presidential Award, Morphine inhibits immune function: identification of a novel morphine receptor., $2,175.00 2002: 鶹ֱ Presidential Award, The Role of Nutrition and the Mitochondria in the Health of the Nervous SystemPRIVATE tc \l 2 "Introduction", $2,200.00 1997- 2007: Member, National Institutes of Health AIDS Reagent repository, $20,000.00 in the form of reagents. 2007 - 2010 Nature's Value, "Pesticide Toxicity to Soil Microorganisms", $12000.00/year for three years ($36,000.00) 2008 - 2011 Innovation Laboratories, "The Mechanism of Pyrethroid Pesticide Neurotoxicity", $3,000.00/year for 4 years ($12,000.00) 2019 2020 OneInnoveation Labs, The role of TRKA in CBD The role of Cannabidiol-TRKA interactions in neurite outgrowth, T-cell attachment and epithelial cell migration ($15,000.00). Editorial Positions: 2008 2012 Member of the Editorial Board of the journal "Medical Science Monitor". Institutional and Departmental Service: 19901993: Radiation Safety Officer, Laboratory of Developmental Anomalies, National Institutes of Health 1997 2002: Faculty Senate Member, 鶹ֱ 1997: Faculty Senate Executive Committee, 鶹ֱ 1997: Health and Human Services Task Force, 鶹ֱ 1997: Environmental Studies Committee, 鶹ֱ 1997 2005: CoDirector, Committee on Honors and Undergraduate Research, Biology Department, 鶹ֱ 1997: Ad Hoc Committee on Curricular Reform, Biology Department, 鶹ֱ 1998: Faculty Senate Member, 鶹ֱ 1998 Present: Institutional Animal Care and Use Committee, 鶹ֱ 1998 Present: Freshman Advisor, 鶹ֱ 1999 2005: Premedical Advisement Committee, 鶹ֱ 1999 2006: Director of Undergraduate Affairs, Biology Department, 鶹ֱ 2002: College of Arts and Sciences, Curriculum and Academic Affairs Committee, 鶹ֱ 2002: Senate Committee on Curriculum and Academic Affairs, 鶹ֱ 2005 2010: Unit Peer Review Committee, Biology Department, 鶹ֱ 2006 2010: Director of the Joint Adelphi Program with Tufts University of Dental Medicine, Biology Department, 鶹ֱ 2007 2011: Undergraduate Curriculum Committee, Chair, Biology Department, 鶹ֱ 2009-2010: Committee on the Award for Faculty Excellence in Scholarship, Chair 2011-2012: University College Unit Peer Review Committee, Chair 2021: Undergraduate Curriculum Committee, Biology Department, 鶹ֱ; Unit Peer Review Committee, Biology Department, 鶹ֱ Courses Taught: Undergraduate Introduction to Biology, Undergraduate Course no lab, University of Connecticut, (4 semesters as a Teaching Assistant). Histological Micro Techniques, Undergraduate Laboratory Course, University of Connecticut (2 semesters as a Teaching Assistant, the laboratory component). The Modern Myths in Contemporary Popular Music (Gen. Ed. 110), Undergraduate course for general education, 鶹ֱ Current Events in Biology (Gen. Ed. 110), Undergraduate course for general education, 鶹ֱ Biological Concepts and Methods I (Bio. 111), Undergraduate Introductory Laboratory Course, 鶹ֱ Biological Concepts and Methods I (Bio. 112), Undergraduate Introductory Laboratory Course, 鶹ֱ *The Biology of AIDS (Bio.105), Undergraduate Non-majors Course - no lab, 鶹ֱ *Microbes and Society (Bio. 107), Undergraduate Laboratory Course for non-majors, 鶹ֱ Immunology (Bio.360), Undergraduate Laboratory Course, Hamilton College (Half semester course) Developmental Biology (Bio. 225), Undergraduate Laboratory Course, Hamilton College, (Half semester course) Cell Chemistry (Bio. 210), Undergraduate Laboratory Course, Hamilton College, (One third semester course) Nature of Viruses (Bio. 340), Undergraduate Course  no lab, 鶹ֱ Vertebrate Embryology (Bio. 356), Undergraduate Laboratory Course, 鶹ֱ. Fundamental Microbiology, (Bio. 238), Undergraduate Laboratory Course, 鶹ֱ Microbiology for Nurses (Bio. 208), Undergraduate Laboratory Course, 鶹ֱ Molecular Cell Biology (Bio. 336), Undergraduate Laboratory Course, Hamilton College *Developmental Biology (Bio. 345), Undergraduate, full semester laboratory course, 鶹ֱ Biochemistry (Chem. 471), Undergraduate, full semester laboratory course, 鶹ֱ Toxicology (Bio. 485), Undergraduate Course - no lab, 鶹ֱ Science and the Citizen (330), Undergraduate course no lab, served the general education purposes of the adult ABLE program, 鶹ֱ *The Biology of SARS-CoVid-2/CoViD-19 (Bio 105), Undergraduate course, no lab, not for majors credit Graduate Protein Gel Electrophoresis, Graduate MiniCourse, Georgetown University Cell Physiology (Bio. 8151), Graduate Course  no lab, Villanova University Introduction to Molecular Biology (Bio. 506), Graduate Laboratory Course, Adelphi University Immunology (Bio. 528), Graduate Course  no lab, 鶹ֱ *Environmental Pollutants and Disease (Bio. 567), Graduate Course  no lab, Adelphi University Virology (Bio. 670), Graduate Course  no lab, 鶹ֱ *Cell Culture Techniques (Bio. 626), Graduate Laboratory course, 鶹ֱ Biochemistry (Chem. 571), Graduate Laboratory course, 鶹ֱ *Basement Mebrane Biology (Bio. 654), Graduate course no lab, 鶹ֱ Principles of Disease (Bio. 554), Graduate course no lab, 鶹ֱ *New courses proposed, developed, approved and added to the curriculum at 鶹ֱ Conference and Invited Lectures: 1987 1) "Acetaminophen embryotoxicity", Teratology Society, Boston, MA. 2) "The embryotoxicity of antilaminin antibodies in laminin immunized monkeys", Teratology Society, Boca Raton, FL. 3) "The embryotoxicity of antilaminin antibodies in laminin immunized monkeys", National Institutes of Health, NIDR, Laboratory of Developmental Biology and Anomalies, Bethesda, MD. 1989 4) "The role of laminin in neural development", Tokyo Dental School, Tokyo, Japan. 5) "Laminin signal transduction in neuronal cells", East Coast Connective Tissue Conference, Bethesda, MD. 1990 6) Mesangial cell receptors for laminin and laminin binding domains", American Society of Nephrology, Wash. DC. 1991 7) "Laminin signal transduction in neuronal cells", Georgetown University Department of Anatomy, Wash. DC. 1991 8) "Laminin signal transduction in neuronal cells and subsequent gene expression", Weizmann Institute, Department of Neurobiology, Rehovot, Israel. 9) "HIV1 induced integrin and collagenase expression in human T cells", American Society of Nephrology, Baltimore, MD. 10) "Laminin signal transduction in neuronal cells and subsequent gene expression", 15th Congress of Biochemistry, Jerusalem, Israel. 11) "The role of Laminin in the development of the nervous system", 3rd Annual Jerusalem Conference on the Extracellular Matrix, Jerusalem, Israel. 1992 12) "Laminin stimulation of mitochondrial gene expression in neuronal cells", National Institutes of Health, NIA, Laboratory of Neurobiology, Baltimore, MD. 13) "The role of the mitochondria in lamininmediated neurite outgrowth", National Institutes of Health, NIA, Laboratory of Neurobiology, Bethesda, MD. 14) "The role of laminin in neuronal development", Colgate University, Hamilton, NY. 15) "The role of laminin in neuronal development", Skidmore College, Saratoga Springs. NY. 16) "The role of laminin in neuronal development", Utica College, Utica, NY. 17) "HIV1 infection alters immunocyte interaction with the extracellular matrix", The University of Connecticut, Storrs, CT. 1996 18) "The role of the extracellular matrix in development and disease, Villanova University, Villanova, PA 19) "HIV 1 infection alters immunocyte interaction with the extracellular matrix", The Philadelphia College of Textiles and Science, Philadelphia, PA. 1997 20) "The role of the basement membrane in viral pathogenesis", Mount Sinai University, School of Medicine, New York, NY. 21) "Tat neurotoxicity", Allegheny University, Center for Neurovirology, Philadelphia, PA. 1998 22) Leukocytes from HIV-1 Transgenic Mice are Adherent to Extracellular Matrix Proteins, National Conference for Undergraduate Research, University of Rochester, Rochester, NY (presented by an undergraduate student) 23) Laminin-Mediated Neurite Outgrowth Involves Protein Dephosphorylation, National Conference for Undergraduate Research, University of Rochester, Rochester, NY (presented by an undergraduate student) 2000 24) The role of leukocyte adhesion molecules and gelatinases in AIDS pathogenesis, The 3rd International Symposium on Molecular Medicine, Medical School University of Crete, Hersonissos, Crete, Greece 25) "The role of the basement membrane in viral infections", Special Populations Research Development Seminar Series; Opiate Substance Abuse: Potential for HIV Associated Complications, Chicago, IL 26) "The role of the basement membrane in viral infections", SUNY College at Old Westbury, Old Westbury, NY 2001 27) "Laminin1 and the RKRLQVQLSIRT laminin1 a1 globular domain peptide activate nitric oxide production in PC12 cells" 13th International Symposium on Bioscience and Human Technology, National Institute of Bioscience and Human-Technology, Ibaraki, Japan 2002 28) "Laminin1 and the RKRLQVQLSIRT laminin1 a1 globular domain peptide activate nitric oxide production in PC12 cells" Lombardi Cancer Center, Georgetown University Medical Center, Washington D.C. 29) "The role of the extracellular matrix in development and disease", Nassau County Community College, Garden City, NY 2004 30) "The role of the basement membrane in viral infections", SUNY College at Old Westbury, Old Westbury, NY 2006 31) The Biological Effects of Bifenthrin on T-cells and Neurons: A Comparison of Activity, The 1st International Conference on the Conservation and Management of Natural Resourses, Ismailia, Egypt (presented by Dr. Katherine Flynn) 2007 32) "The Discovery and Uses of a Novel Vitamin C Preparation: PureWay-C"!",  HYPERLINK "http://www.bodycotetesting.com/Category.aspx?ContId=13978&CatId=11165" Supply Side West 2007, Las Vegas, NV 2008 33) "Positive Effects of PureWay-C on a Marker of Oxidative Stress and Biomarkers of Inflammation", Supply Side East, 2008, Secaucus, NJ 34) The Mechanism of Pyrethroid Pesticide Neurotoxicity, The University Club, Garden City, NY 2019 35) The role of Cannabidiol-TRKA interactions in neurite outgrowth, Supply Side West 2019, Las Vegas, NV 2021 36) Neurotrophic anxiolytic phytochemicals in food and dietary supplements promote neuronal survival and neuroplasticity, e.g., cannabidiol binds TRKA and promotes neurite outgrowth, International Conference on Neuroscience and Psychiatry 2021 Vienna, Austria. Poster Presentations: "Teratogenicity of antilaminin antibodies", Teratology Society, Palm Beach, FL. "Antilaminin antibody embryotoxicity", Teratology Society, Boston, MA. 3) "Laminin signal transduction in neuronal cells", 7th International Conference on Cyclic Nucleotides, Calcium, and Protein Phosphorylation, Kobe, Japan. 4) "Laminin signal transduction in neuronal cells", American Society of Cell Biology (ASCB), Houston, TX. 5) "Laminin induction of a novel leucine zipper transcription factor, National Institutes of Health Research Day, Bethesda, MD. 1990 6) "Laminin signal transduction in neuronal cells", American Society of Cell Biology (ASCB), San Diego, CA. "The role of laminin in neural development", American Society of Cell Biology (ASCB), San Diego, CA. "The role of laminin in sertoli cell differentiation", American Society of Cell Biology (ASCB), San Diego, CA. "The expression of integrins on HIV1 infected human lymphocytes", American Society of Cell Biology (ASCB), San Diego, CA. "Alzheimer brain extract induction of neurite outgrowth in PC 12 cells", National Institutes Of Health Research Day, Bethesda, MD 11) "Alzheimer brain extract induction of neurite outgrowth", Society for Neurosciences, St. Louis, MI. 12) "HIV1 induction of integrins in human T cells", Annual Meeting of the Laboratory Of Tumor Cell Biology, Bethesda, MD. 1991 13) "Nephropathy in HIV1 transgenic mice" (Henry Christian Award Winner), American Federation Of Clinical Research, Seattle, WA. 14) "HIV1 associated nephropathy in transgenic mice", Seventh International Conference On AIDS, Florence, Italy. 15) "Cell binding domains on the HIV I tat protein and a 90 kDa Tat binding protein"Annual Meeting of the Laboratory of Tumor Cell Biology, Bethesda, MD. 16) "HIV1 induction of integrins in human Tcells", Annual Meeting of the Laboratory of Tumor Cell Biology, Bethesda, MD. 17) "The domain specificity of embryotoxic antilaminin antibodies", Teratology SocietyBoston. MA. 1992 18) "Transgenic animals as a model of HIV1 pathology", Annual Meeting of the Laboratory of Tumor Cell Biology, Bethesda, MD. 19) "bFGF in the pathogenesis of AIDSassociated nephropathy", American Society of Nephrology, Baltimore, MD. 20) "Laminin induced expression of mitochondrial genes", Foundation for the Advancement of Education in Science, National Institutes of Health, Bethesda, MD. 1993 21) "The role of bFGF in HIV1 associated nephropathy in transgenic mice.", American Society of Nephrology, Baltimore, MD. 22) "bAmyloid precursor protein binds to the IKVAV site of laminin.", Society for Neurosciences, Washington, D.C. 23) "bAmyloid precursor protein binds to the IKVAV site of laminin.", American Society of Cell Biology, New Orleans, Louisiana. 1994 24) "Lymphocytes and promonocytes attach to the polypherneusin 11 peptide (T22)."American Society of Cell Biology, San Francisco, CA. 25) "Phosphatase inhibitors promote immunocyte homotypic aggregation.", American Society of Cell Biology, San Francisco, CA. 26) "AIDS associated Kaposis Sarcoma Cells Secrete a Neurotrophic Factor, Keystone Symposia Meetings on HIV I Pathogenesis, Keystone, CO 27) "Adhesion to extracellular matrix proteins by lymphocytes isolated from HIV 1 Transgenic mice.", Keystone Symposia Meetings on HIV I Pathogenesis, Keystone, CO 28) "HIV1 transgenic mice: A model of AIDS associated neurological dysfunction?, The Twentieth Annual Biological Sciences Research Symposium, Binghamton University, Binghamton, NY 29) "AIDS associated Kaposis sarcoma cells secrete a neurotrophic factor(s).", The Thirtieth Annual Sigma Xi Poster Session at Hamilton College, Clinton, NY 30) "Tyrosine kinase inhibitors promote lamininmediated neurite outgrowth.", The Thirtieth Annual Sigma Xi Poster Session at Hamilton College, Clinton, NY 31) "HIV1 transgenic mice: A model of AIDS associated neurological dysfunction?", The Thirtieth Annual Sigma Xi Poster Session at Hamilton College, Clinton, NY 32) "The HIV 1 transactivator of transcription, Tat, activates apoptosis in neuronal cells and the central nervous system.", The Thirtieth Annual Sigma Xi Poster Session at Hamilton College, Clinton, NY 1996 33) "The polyphemeusin T22 peptide is recognized by the CD4 cell surface molecule.", Annual Scientific Symposium and Retreat, Cancer Center, University of Pennsylvania, Philadelphia, PA 34) "bFGF stimulates monocyte adhesion to fibronectin.", Annual Scientific Symposium and Retreat, Cancer Center, University of Pennsylvania, Philadelphia, PA 35) " The herpes simplex virus type I glycoprotein E domains involved in IgG binding and cell tocell spread do not comap.", Annual Scientific Symposium and Retreat, Cancer Center, University of Pennsylvania, Philadelphia, PA 36) "The polyphemeusin T22 peptide is recognized by the CD4 cell surface molecule.", The second annual Sigma Xi Poster Session at Thomas Jefferson Medical College, Philadelphia, PA (first place award) 37) "bFGF stimulates monocyte adhesion to fibronectin." American Society for Women in the Sciences, Philadelphia, PA 38) "The polyphemeusin T22 peptide is recognized by the CD4 cell surface molecule." St. Joseph's University Seventh Annual Poster Session, Philadelphia, PA 39) "Characterization of herpes simplex type1 mutants: The glycoprotein E domains involved in IgG binding and celltocell spread do not comap. "The 21st International Workshop on Herpes Virus, DeKalb, IL 40) "bFGF stimulates monocyte adhesion to fibronectin." American Society of Cell Biology, San Francisco, CA. 1997 41)"Evidence for a role for the HSV1 Fc receptor In Vivo.", The 22nd International Workshop on Herpes Virus, DeKalb, IL 42) "Laminin and agrin cluster postsynaptic acetylcholine receptors". The 28th Annual Meeting of the Society for Neurosciences. Los Angeles, CA. 1999 43) Laminin and the RKRLQVQLSIRT laminin derived synthetic peptide stimulate nitric oxide production in PC12 cells, American Society for Cell Biology, Washington D.C. 44) Agrin and laminin activate Rac during acetylcholine receptor clustering, American Society for Cell Biology, Washington D.C. 45) Cdc42 is activation is required for laminin-mediated neurite outgrowth, American Society for Cell Biology, Washington D.C. 2000 46) "Morphine inhibits indolactam V-induced U937 cell adhesion and gelatinase secretion". American Society for Cell Biology, San Fransisco, CA. 47) "Agrin and laminin activate Rac during acetylcholine receptor clustering". American Society for Cell Biology, San Fransisco, CA. 2001 48) "Agrin and Laminin signal through the Rho GTPase during actetylcholine receptor clustering". American Society for Cell Biology, Washington D.C. 2002 49) "Agrin and Laminin signal through the Rho GTPase during actetylcholine receptor clustering". American Society for Cell Biology, San Fransisco, CA. 2006 50) The pesticide atrazine results in estrogen-like alteration of spatial distribution in freshwater mussels., The SAFE Consortium International Congress on Food Safety, Budapest, Hungary 51) Bifenthrin inhibits neurite outgrowth in differentiating PC12 cells. The SAFE Consortium International Congress on Food Safety, Budapest, Hungary 52) "Estrogenic effects of bifenthrin, a synthetic pyrethroid, on Corbicula fluminea." SETAC North America 27th Annual Meeting, Montreal, Canada 2017 53) Anagnostis P. AGELARAKIS, Argiro AGELARAKIS & Benjamin WEEKS The Poultice Recommended for Surgical Interventions on Head Wounds in the Hippocratic Corpus. Did it Work? 44th Annual North American Meeting, NEW ORLEANS April , 2017 Publications (Not Peer-Reviewed): *Doscher, J and B. S. Weeks. The World-Wide AIDS Epidempic, ISSAC, 2: 25-27, 2003 Weeks, B.S. A Heros Journey to Simple Shelter: A Prose Poem, The Improper Hamptonian, 1: 29, 2003 Selenium: A nutrient like no other. Life extension magazine, 2011 Aniety Protocol. Life extension magazine, 2011 *graduate student co-author Peer-Reviewed Publications: 1. Rubenstein, E.C., T. J. Kelly, L. Clubert, CW. Woods, and B. Weeks. Ecdysteroids in developing ovarian follicles of Hyalophora cecropia. Arch. of Insect Biochem. and Physiol., 3: 253263, 1986 2. Weeks, B.S. and N.W. Klein. In vitro and in vivo embryo toxicity of antilaminin antibodies in the rat. Am. J. Reprod. Immunol., 19: 5764, 1989 3. Weeks, B.S., N.W. Klein, H.K. Kleinman, T. Fredrickson, and G.P. Sackett. Laminin immunized monkeys develop sera toxic to cultured rat embryos and fail to reproduce. Teratology, 40: 4757, 1989 4. Tashiro, K., G.C. Sephel, B. Weeks, M. Sasaki, G.R. Martin, H.K. Kleinman, and Y. Yamada. A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth. J. Biol. Chem., 264:1617416182, 1989 5. Kleinman, H.K. and B.S. Weeks. Laminin: structure, functions, and receptors. Current Opinion in Cell Biol., 1: 964967, 1989 6. Weeks, B.S., Kopp, J., Horikoshi, S. Cannon, F.B. *Garrett, M. Kleinman, H.K. and P.E. Klotman. Renal cells interact with specific laminin domains via developmentally regulated binding proteins. Am. J. Physiol., 261: 688695, 1990 7. Weeks, B.S., *Gamache, P., Klein N.W., Hinson, J.A., Bruno, M., and E. Khairallah. Acetaminophen toxicity to cultured rat embryos. TCM, 10: 361 370, 1990 8. Hadley, M.A., B.S. Weeks, H.K. Kleinman, and M.Dym. Laminin promotes tubule formation by cultured Sertoli cells. Dev. Biol., 140:318327, 1990 9. Weeks, B., V. Papadopoulos, M. Dym, and H.K. Kleinman. cAMP promotes branching of laminininduced neuronal processes. J. Cellul. Physiol., 147: 6267, 1990 10. Kleinman, H.K., M.C. Kibbey, F.B. Cannon, B.S. Weeks, and D.S. Grant. Techniques for use of extracellular matrix in culture, In Extracellular Matrix Molecules. A Practical Approach. (eds. M.A. Haralson and J.R. Hassell), Oxford Univ. Press, 1990 11. Kleinman, H.K., B.S. Weeks, F.B. Cannon, T.M. Sweeney, G.C. Sephel, B. Clement, M. Zain, O.J. Olson, M. Jucker, and B. Burrous. Identification of a 110 Kd nonintegrin neurite promoting peptide: homology with nucleolin. Arch. Biochem. Biophys., 290: 220225, 1990 12. Kleinman, H.K., G.C. Sephel, K. Tashiro, B.S. Weeks, B.A. Burrows, S.H. Adler, Y. Yamada, and G.R. Martin. Laminin in neuronal development. N.Y. Acad. Sci., 580: 302310, 1990 13. Kleinman, H.K. and B.S. Weeks. Laminin in Neuronal Development. Encyclopedia of Human Biology, Ed. R. Dulbecco, Academic Press Inc, N.Y., 4: 623631, 1990 14. Weeks, B.S., J. DiSalvo, and H.K. Kleinman. Laminin mediated neurite outgrowth involves protein dephosphorylation. J. Neurosci. Res., 27: 418426, 1990 15. Kleinman, H.K., and B.S. Weeks. The neural cell response to laminin: Active sites, receptors, and intracellular signals. Comments on Devel. Neurobiol., 1: 251266, 1991 16. Weeks, B. S., M. E. Klotman, M. Kibbey, H. K. Kleinman, K. Yamada, P. E. Klotman. HIV1 induced expression of integrin on human CD4+lymphocytes. J. Cell Biol., 114:847853, 1991 17. Kittur, S., W. Adler, G. Martin, H. Kleinman, and B, Weeks. Neurotrophic effects of Alzheimers brain homogenate and cerebrospinal fluid on neuronal cell cultures. Alzheimer Disease and Associated Disorders, 6: 103110, 1992 18. Kinsella, J. L., Grant, D. S., Weeks, B. S., and Kleinman, H. K. Protein kinase C regulates endothelial cell tube formation on basement membrane Matrigel. Exp. Cell. Res., 199: 5662, 1992 19. Paralkar, V. M., Weeks, B. S., Yu, Y., Kleinman, H. K., and Reddi, A. H. Neurotrophic effects of bone morphogenic protein 2B and activin. J. Cell Biol., 119:17211728, 1992. 20. Burbello P., Gabriel G., Wujeck J., Kedar V. V., Weeks B. S., Klienman H. K., and Yamada Y., Basement membrane genes and transcription factors. Cellular and Molecular Aspects of Cirrhosis, 216: 135145, 1992 21. Dhawan, S., Weeks, B. S., Klotman, M. E., and Klotman, P. E. Increased expression of a4bI and a5bl integrins on HTLV1Infected Lymphocytes. Virology, 197: 778781, 1993 22. Weeks, B. S., Schnaper, W. H., *Holloway, E., and Kleinman, H. K. Human Tcells synthesize the 92 kDa type IV collagenase (gelatinase B) J. Cellular. Phys., 157: 644, 1993 23. Kibbey, M. C., Jucker M., Weeks B. S., and Kleinman, H. K. beta-Amyloid precursor protein binds to the IKVAV site of laminin. Proc. Natl. Acad. Sci., 90: 9195, 1993 24. Weeks B. S., Klotman M. E., Holloway E., StetlerStevenson W. G., Kleinman H. K., and P.E. Klotman. HIV 1 infection stimulates Tcell invasiveness and synthesis of the 92 kDa type IV collagenase. AIDS Res. Hum. Retroviruses, 9: 513518, 1993 25. Weeks B. S., Desai K., Lowenstien P. M., Holloway E., Klotman M. E., Klotman P. E., Green M., and Kleinman H. K. Identification of a novel cell attachment domain in the HIV I Tat protien and its 90 kDa cell surface binding protein. J. Biol. Chem., 268: 52795284, 1993 26. Kleinman, H. K., Weeks B. S., Schnaper H. W., Kibbey M. C., Yamamura K., and D. S. Grant. The Laminins: A family of basement membrane glycoproteins important in cell differentiation and tumor metastases. Vitamins and Hormones, 43:161186, 1993 27. Wahl, S. M., Allen, J. B., Weeks, B. S., Wong, H. L., and Klotman P. E. TGFb enhances integrin expression and type IV collagenase secretion in human monocytes. 90:45774581, Proc. National. Acad. Sci. 1993 28. Weeks, B, Nomizu, M, *Okusu, A., *Weston, C., and N. Fuji. Lymphocytes and promonocytes attach to the polyphemusin peptide J22). Biochem. Biophys. Res. Commun., 202:470475, 1994 29. Weeks, B. S., Schnaper, W. H., *Holloway, E., Klotman P. E., and Kleinman, H. K. 120Teteradecanoylphorbol 13acetate stimulates Human T lymphocyte adherence to the fibronectin RGD domain and the laminin IKVAV domain. Cell. Immunol., 153: 94104,1994 30. Burbello, P., B.S. Weeks, Y. Yamada, and H.K. Kleinman. LZIP I and LZIP2: two novel members of the bZIP family. Gene, 139: 241245, 1994 31. Ferrari D. A., Gilles P. A., Klein N. W., Weeks B. S., LammiKeefe C., Hillman R. E., Ying YK., Maier D., Olsen P., Wemple D. W., Greenstein R., Muechler E. K., Miller R. K., and Mariona F. G., Rat embryo development on human sera is related to numbers of previous spontaneous abortions and nutritional factors. J. Obstet. Gynacol., 170: 228236, 1994 32. Kittur, S., Endo, H., Hoh, J., Tourtellotte, W., Weeks, B., Markesbery, W., and Adler, W. Cytoskeletal neurofilament gene expression in brain tissue from Alzheimer's disease patients, Journal of Geriatric Psychiatry and Neurology, 7: 153158, 1994 33. Ray, P., Bruggeman L., Weeks B., and P. E. Klotman. bFGF and its low affinity receptors in the pathogenesis of HIVassociated nephropathy in transgenic mice. Kidney International, 46: 759772, 1994 34. Weeks, B., *Weston, C., *Okusu, A., Nomizu, M., and N. Fujii. The polypherneusin T22 peptide is recognized by the CD4 cell surface molecule. Biochem. Biophys. Res. Commun., 215: 626631, 1995 35. Nomizu, M., Weeks, B.S., *Weston, C.A., W. W. Kim, H. K. Kleinman and Y. Yamada. StructureActivity study of a laminin al chain active peptide segment IleLysValAlaVal (IKVAV). FEBS letters, 365: 227231, 1995 36. Dhawan, S., B. Weeks, H. W. Schnaper, K. Yamada, S. Yamada, and M. Meltzer. HIV I infection alters monocyte interaction with endothelial cell layers. J. Immunol., 154: 422432, 1995 37. Weeks, B., Oldfield, E. and H. Kleinman. Neurotoxicity of the HIV I Tat transactivator to PC 12 cells requires the Tat amino acid 4958 basic domain. J. Neuroscience Res., 42: 3440, 1995 38. Chambers, B., G. Sackett, B. Weeks, H. K. Kleinman, and N. Klein. In vivo and in vitro embryotoxicity of domain specific antilaminin antibodies. Proc. Natl. Acad Sci., 90: 68186822, 1995 39. *Weston, C.A. and B.S. Weeks. bFGF stimulates U937 cell adhesion to fibronectin. Biochem. Biophys. Res. Commun., 228: 318323, 1996 40. Weeks, B.S. and *J. luorno. Phosphatase inhibitors stimulate ICAM I and LFA I mediated aggregation of Tlymphocytes. Biochem. Biophys. Res. Commun., 226: 8287, 1996 41. Weeks, B, Burbello, P., *Weiner, M. and H. Kleinman. Laminin stimulates the expression of two mitochondrial proteins. Int. J. Dev. Neurosci. 14: 365374, 1996 42. Weeks, B., and H. Friedman. Laminin reduces, the celltocell spread of HSV I in human keratinocyte cultures. Biochem. Biophys. Res. Commun. 203: 466469, 1997 43. Saswata, B., Dubin, G., Basu, M., Weeks, B., and H. Friedman. Characterization of regions of herpes simplex virus type I glycoprotein I that form an FcR with glycoprotein E for binding monomeric IgG. J. Immunol. 158: 209215, 1997 44. Weeks, B.S. and *R. Cooney. AIDS associated Kaposis sarcoma cells secrete a neurotrophic factor(s). Biochem. Biophys. Res. Commun. 233: 408412, 1997 45. Weeks, B.S., Sundaresan, P., Nagashunmugam, T., Kang, E. and H.M. Friedman. The herpes simplex virus1 glycoprotein E (gE) mediates IgG binding and celltocell spread through distinct gE domains. Biochem. Biophys. Res. Commun. 235: 3135, 1997 46. Kleinman, H.K., Weeks, B.S. Richard, B.L., and M.C. Kibbey, Laminin in neuronal development. Encyclopedia of Human Biology, Ed. R. Dulbecco, Academic Press Inc, N.Y., 5: 227235, 1997 47. Nagashunmugam, T., Sundaresian, P., Weeks, B., Goldstein, L., and H. Friedman. Characterization of herpes simplex type1 mutants: The glycoprotein E domains involved in IgG binding and celltocell spread do not comap. J. Virol., 72: 53515359, 1998 48. Weeks, B.S., The role of leukocyte adhesion and matrix metalloproieinase secretion in AIDS pathogenesis. Int. J. Molec. Med., 1: 361366. 1998 49. Weeks, B.S., Nomizu, M., *Ramchandran, R.S., Yamada, Y., and H.K. Kleinman. Laminin1 and the RKRLQVQLSIRT laminin1 a 1 globular domain peptide stimulate matrix metalloproteinase secretion by PC12 cells. Exp. Cell Res., 243: 375382, 1998 50. Weeks, B.S., *Wilson, P.J., Heffernan, C.C., *Ahmad, A., and *K. Mahadeo. The role of protein kinase C in laminin-mediated neurite outgrowth. Biochem. Biophys. Res. Commun. 256: 98 103, 1999 51. Weeks, B.S., *Wilson, P.J., Heffernan, C.C., Gorra, V.A., White, L.E. and *A. Ahmad. Laminin stimulates protein tyrosine dephosphorylation in PC12 cells. Biochem. Biophys. Res. Commun. 262: 713-719, 1999 52. **Gavriil, E.S., *Cooney, R., and B.S. Weeks. Tat mediates apoptosis in vivo in the rat central nervous system. Biochem. Biophys. Res. Commun. 267:252-256, 2000 53. Weeks, B.S., *Ramchandran, R., ** Hopkins, J. and H.F. Friedman. HSV-1 and  2 pathogenesis is restricted by the epidermal basement membrane. Arch. Virol., 145: 385-396, 2000 54. Rialas C.M., Cadet P., Weeks B., Salzet M., and G.B. Stefano. Nociceptin, endomorphin-1 and 2 do not bind to the invertebrate immune m3 Opiate Receptor Subtype. Acta Pharmacol. Sin, 21: 516-520, 2000 55. Stefano, G.B., Weeks, B.S., and P. Cadet. GP120 Promotes HIV Survival by Distracting Immune Surveillance. Mod. Aspects of Immunobiology, 1: 63 - 68, 2000 56. Goumon, Y., B.S. Weeks, *M. Bougeava, F. Caseres, P. Cadet and G.B. Stefano. Identification of Morphine in the Adrenal Medullary Chromaffin PC12 cell line. Molec Brain Res., 81: 177-180, 2000 57. Rialas C.M., *Patterson, M., Weston, C., and B.S. Weeks. Laminin1 and the RKRLQVQLSIRT laminin1 a 1 globular domain peptide activate nitric oxide production in PC12 cells. Exp. Cell Res., 260:268-276, 2000 58. Weston, C., Prives, Rials, C., *Anova, L., and B.S. Weeks. Laminin activation of Cdc42 is required in the mechanism of laminin-mediated neurite outgrowth. Exp. Cell Res., 260: 274 - 378, 2000 59. Cadet, P., B.S. Weeks, Bilfinger, T.V., Casares, F., and G.B. Stefano. gp120 and Morphine Alter Mu Opiate Receptor Expression in Human Blood Vessel Endothelium. Int J Mol Med. 8:165-169, 2001 60. Weeks, B.S., **Ninche Alston, and G.B. Stefano Morphine reduces HSV-1 lesion sized in mice. Int J. Molec Med. 8:303-307, 2001 61. Weeks, B.S., Cadet, P., Touma, S., *Goldman, S., *Payne, M., and G. Stefano. Morphine inhibits indolactam V-induced U937 cell adhesion and gelatinase secretion. J. Cell Physiol. 189: 179-188, 2001 62. M. Makino, I. Okazaki, N. Nishi, *M Bougaeva, B. Weeks, A. Otaka, P. K. Nielsen, Y Yamada, and M. Nomizu. Identification of Cell Binding Sites in the Laminin Alpha 5 Chain G domain. Exp. Cell Res., 277: 95 - 106, 2002 63. ** Nandi A. and B.S. Weeks. A model for the mechanism of laminin-mediated neurite outgrowth. Cur. Top. in Pep. and Prot. Res., 7, 47-51, 2005 64. ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Hoffman+N%22%5BAuthor%5D" \o "Click to search for citations by this author." Hoffman N, ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Tran+V%22%5BAuthor%5D" \o "Click to search for citations by this author." Tran V, ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Daniyan+A%22%5BAuthor%5D" \o "Click to search for citations by this author." Daniyan A,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Ojugbele+O%22%5BAuthor%5D" \o "Click to search for citations by this author." Ojugbele O,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Pryor+SC%22%5BAuthor%5D" \o "Click to search for citations by this author." Pryor SC, ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Bonventre+JA%22%5BAuthor%5D" \o "Click to search for citations by this author." Bonventre JA,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Flynn+K%22%5BAuthor%5D" \o "Click to search for citations by this author." Flynn K,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Weeks+BS%22%5BAuthor%5D" \o "Click to search for citations by this author." Weeks BS. Bifenthrin activates homotypic aggregation in human T-cell lines.  HYPERLINK "javascript:AL_get(this,%20'jour',%20'Med%20Sci%20Monit.');" Med Sci Monit. 2006 Mar;12(3):BR87-94, 2006 65. ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Tran+V%22%5BAuthor%5D" \o "Click to search for citations by this author." Tran V, ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Hoffman+N%22%5BAuthor%5D" \o "Click to search for citations by this author." Hoffman N, ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Mofunanaya+A%22%5BAuthor%5D" \o "Click to search for citations by this author." Mofunanaya A,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Pryor+SC%22%5BAuthor%5D" \o "Click to search for citations by this author." Pryor SC,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Ojugbele+O%22%5BAuthor%5D" \o "Click to search for citations by this author." Ojugbele O,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22McLaughlin+A%22%5BAuthor%5D" \o "Click to search for citations by this author." McLaughlin A,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Gibson+L%22%5BAuthor%5D" \o "Click to search for citations by this author." Gibson L, ** HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Bonventre+JA%22%5BAuthor%5D" \o "Click to search for citations by this author." Bonventre JA,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Flynn+K%22%5BAuthor%5D" \o "Click to search for citations by this author." Flynn K,  HYPERLINK "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Weeks+BS%22%5BAuthor%5D" \o "Click to search for citations by this author." Weeks BS. Bifenthrin inhibits neurite outgrowth in differentiating PC12 cells.  HYPERLINK "javascript:AL_get(this,%20'jour',%20'Med%20Sci%20Monit.');" Med Sci Monit. 12 (2):BR57-62, 2006 66. **Nandi A., *Chandi D., **Lechesa R., Pryor SC., McLaughlin A., **Bonventre JA., Flynn K., and B. S. Weeks. Bifenthrin causes neurite retraction in the absence of cell death: A Model for Pesticide Neurodegeneration. Med Sci. Monit. 12,(5):BR169- 173, 2006 67. **Nandi A., *Chandi D., *Thurber C., *DeLuca L, Pryor SC., McLaughlin A, Gibson L, **Bonventre JA., Flynn K, and BS. Weeks. The Biological Effects of Bifenthrin on T-cells and Neurons: A Comparison of Activity. CATRINA, 1 (1) 9 - 14, 2006 68. Weeks, B., and P. Perez. PolicosanolPlus and neuroprevin enhance neurite regeneration and prevent neurite degeneration: Dietary supplements for nerve repair and prevention, and reduction of neurodegenerative disorders. JANA, 9(2) 24 - 29, 2006 69. Weeks, B and P. Perez., PolicosanolPlus and NeuroprevinTM Ameliorate Pesticide-Mediated Inhibition of Neurite Outgrowth Neurite Degeneration. Med. Sci. Monit, Medical Science Monitor, 12(12) 379-384, 2006 70. Weeks, B and P. Perez., A novel vitamin C preparation enhances neurite formation and fibroblast adhesion and reduces xenobiotic-induced T-cell hyperactivation. Medical Science Monitor, 13(3):BR51-58, 2007 71. Weston C.A., G. Teressa, B.S. Weeks, and J. Prives. Agrin and Laminin Induce Acetylcholine Receptor Clustering by Convergent, Rho GTPase-dependent Signaling Pathways, Journal of Cell Science, 120(5):868-75, 2007 72. Weeks, B.S. and P. Perez. Absorption rates and free radical scavenging values of vitamin C-lipid metabolites in human lymphoblastic cells. Med Sci Monit 10:205-210, 2007. 73. Weeks, B., **Lee S.W., Perez, P., **Brown K., **Chauhan, H., and **T. Tsaava. Natramune"! and PureWay-C reduce xenobiotic-induced human T-cell a5b1 integrin-mediated adhesion to fibronectin. Medical Science Monitor, 14(12):BR279-285, 2008 74. Weeks, B and P. Perez. The hemicellulose preparation, (Natramune"! (PDS-2865), increases macrophage phagocytosis and nitric oxide production and increases circulating human lymphocytes levels. Med Sci Monit. 15(2):BR43-46, 2009 75. Weeks BS,  HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19865069" Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian.Med Sci Monit. 15(11):RA256-62, 2009 76. Lorenson**L, DeSantis** A, Mannath** T, Mirza** F, Weeks BS  HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/20980950" The antimicrobial and phagocytic defense mechanisms of the terrestrial gastropod Lehmannia nyctelia against Escherichia coli and Staphylococcus aureus.Med Sci Monit.16(11):BR339-46, 2010 77. 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S Weeks. Dietary and botanical anxiolytics. Med Sci Monit 18(4):RA40-48, 2012 78. BS. Weeks, Hanna MS*, and D. Cooperstein. Dietary Selenium and Selenoprotein Function. Med Sci Monit. 18(8):127-132, 2012 79) Flynn K, Belopolsky M, Dillon-White M, Hines J, Bonventre JA, Weeks BS, Andr C., Schreibman MP and F. Gagn. Burrowing in the freshwater mussel Elliptio complanata is sexually dimorphic and feminized by low levels of atrazine. J Toxicol Environ Health A.;76(20):1168-81., 2013 80) Chakraborty TR, Cohen J*, Yohanan D**, Alicea E*, Weeks BS, Chakraborty S.Estrogen is neuroprotective against hypoglycemic injury in murine N38 hypothalamic cells. Mol Med Rep. Dec;14(6):5677-5684., 2016 81) Agelarakis A, Agelarakis A and B. Weeks, Investigation on the nature, preparation, and medical effectiveness of the Hippocratic cataplasms potentially used in the treatment of head trauma among warriors in Eleutherna and elsewhere in ancient Greece", In press 2022 *indicates undergraduate student coauthors who worked directly under my supervision. ** indicates graduate student coauthors who worked directly under my supervision. Book Chapters: 1)Kleinman, H.K., M.C. Kibbey, F.B. Cannon, B.S. Weeks, and D.S. Grant. Use of extracellular matrix and its components in culture., In: Extracellular Matrix Molecules. A Practical Approach. (eds. M.A. Haralson and J.R. Hassell), Oxford Univ. Press, 1995 2)Weeks, BS, *Weeks SD, *Kim A. *Kessler L. and P.P. Perez, Physiological and Cellular Targets of Neurotrophic Anxiolytic Phytochemicals in Food and Dietary Supplements, Functional Food, InTech Open, ISBN: 978-1-83968-933-8, 2021 *indicates undergraduate student coauthors who worked directly under my supervision. Books: B.S. Weeks and I.E. Alcamo. AIDS: The Biological Basis, 4th Edition, Jones and Bartlett Publishers, Sudbury, MA, 2006 B.S. Weeks and I.E. Alcamo. AIDS: The Biological Basis, 5th Edition, Jones and Bartlett Publishers, Sudbury, MA, 2010 B.S. Weeks and Teri Shorrs. AIDS: The Biological Basis, 6th Edition, Jones and Bartlett Publishers, Sudbury, MA, 2013 B.S. Weeks and I.E. Alcamo. Microbes and Society, 2nd Edition, Jones and Bartlett Publishers, Sudbury, MA, 2007 B.S. Weeks. Microbes and Society, 3rd Edition, Jones and Bartlett Publishers, Sudbury, MA, 2011     Curriculum Vitae Benjamin S. 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